Molecule Details
| InChIKey | KQRNWDALNMUUOG-UHFFFAOYSA-N |
|---|---|
| Compound Name | Cyclobut-1-en-1-yl(3-(1-(4-(trifluoromethoxy)phenyl)-1H-pyrazolo[3,4-b]pyrazin-3-yl)azetidin-1-yl)methanone |
| Canonical SMILES | O=C(C1=CCC1)N1CC(c2nn(-c3ccc(OC(F)(F)F)cc3)c3nccnc23)C1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.08 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q15561 | TEAD4 | Homo sapiens | Human | PF01285 PF17725 | 8.3 | IC50 | BindingDB |
| Q15562 | TEAD2 | Homo sapiens | Human | PF01285 PF17725 | 8.1 | IC50 | BindingDB |
| Q99594 | TEAD3 | Homo sapiens | Human | PF01285 PF17725 | 8.0 | IC50 | BindingDB |
| P28347 | TEAD1 | Homo sapiens | Human | PF01285 PF17725 | 8.0 | IC50 | BindingDB |