Molecule Details
InChIKeyKQDRVXQXKZXMHP-LLVKDONJSA-N
Canonical SMILESCC(C)Cc1ccc([C@@H](C)C(=O)NS(C)(=O)=O)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL8.64
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB12614
Drug NameReparixin
CAS Number266359-83-5
Groups investigational
ATC Codes nan
DescriptionReparixin has been used in trials studying the treatment and prevention of Breast Cancer, Metastatic Breast Cancer, Pancreatectomy for Chronic Pancreatitis, Islet Transplantation in Diabetes Mellitus Type 1, and Pancreatic Islet Transplantation in Type 1 Diabetes Mellitus.

Categories: Amides Sulfones Sulfur Compounds
Cross-references: BindingDB: 50169045 CHEMBL191413 ChemSpider: 8014432 PubChem:9838712 PubChem:347828828 ZINC: ZINC000000008717
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P25024 CXCR1 Homo sapiens Human PF00001 9.0 IC50 ChEMBL;BindingDB
P25025 CXCR2 Homo sapiens Human PF00001 8.3 IC50 ChEMBL;BindingDB
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P25024 CXCR1 C-X-C chemokine receptor type 1 modulator targets
P25025 CXCR2 C-X-C chemokine receptor type 2 modulator targets