Target not found.
Molecule Details
InChIKeyKPWWFNXRLAAREN-UHFFFAOYSA-N
Compound NameNeo2734
Canonical SMILESCc1cc(-c2ccc3nc(C4CCOCC4)n(CCOC(F)(F)F)c3c2)cn(C)c1=O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)12
Pfam Stratification Homologous
Avg pChEMBL7.43
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (12)
Target Gene Organism Category Pfam pChEMBL Type Source
Q15059 BRD3 Homo sapiens Human PF17035 PF00439 8.5 Kd ChEMBL
P25440 BRD2 Homo sapiens Human PF17035 PF00439 8.3 Kd ChEMBL
Q58F21 BRDT Homo sapiens Human PF17035 PF17105 PF00439 8.1 Kd ChEMBL
Q92793 CREBBP Homo sapiens Human PF00439 PF09030 PF08214 PF02172 PF23570 PF06001 PF02135 PF00569 7.7 Kd ChEMBL
Q09472 EP300 Homo sapiens Human PF00439 PF09030 PF08214 PF02172 PF23570 PF06001 PF02135 PF00569 7.6 Kd ChEMBL
Q9BXF3 CECR2 Homo sapiens Human PF00439 7.4 Kd ChEMBL
Q9H8M2 BRD9 Homo sapiens Human PF00439 PF12024 7.2 Kd ChEMBL
P55201 BRPF1 Homo sapiens Human PF00439 PF10513 PF13831 PF00855 PF13832 7.0 Kd ChEMBL
P21675 TAF1 Homo sapiens Human PF00439 PF12157 PF09247 PF15288 7.0 Kd ChEMBL
O60885 BRD4 Homo sapiens Human PF17035 PF17105 PF00439 6.8 IC50 ChEMBL;BindingDB
Q9UIF9 BAZ2A Homo sapiens Human PF00439 PF02791 PF01429 PF00628 PF15612 PF15613 6.8 Kd ChEMBL
Q9UIF8 BAZ2B Homo sapiens Human PF00439 PF02791 PF01429 PF00628 PF15613 6.7 Kd ChEMBL