2-(4-cyanoanilino)-N-(4-phenylpyridin-3-yl)pyrimidine-4-carboxamide

InChIKey	`KOZNFQBNKITETG-UHFFFAOYSA-N`
Compound Name	2-(4-cyanoanilino)-N-(4-phenylpyridin-3-yl)pyrimidine-4-carboxamide
Canonical SMILES	`N#Cc1ccc(Nc2nccc(C(=O)Nc3cnccc3-c3ccccc3)n2)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	9.07
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P49841	GSK3B	Homo sapiens	Human	PF00069	9.8	IC50	ChEMBL
P49840	GSK3A	Homo sapiens	Human	PF00069	9.5	IC50	ChEMBL
P10636	MAPT	Homo sapiens	Human	PF00418	7.9	IC50	ChEMBL