Molecule Details
InChIKeyKOZFSFOOLUUIGY-IYYJOCMQSA-N
Compound NameK-252a, Nocardiopsis sp.
Canonical SMILESCOC(=O)[C@]1(O)C[C@@H]2O[C@@]1(C)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)26
Pfam Stratification Cross-Family
Avg pChEMBL6.98
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (26)
Target Gene Organism Category Pfam pChEMBL Type Source
Q96RR4 CAMKK2 Homo sapiens Human PF00069 8.7 Ki ChEMBL;BindingDB
P04629 NTRK1 Homo sapiens Human PF13855 PF16920 PF07714 PF18613 7.9 IC50 ChEMBL
Q16584 MAP3K11 Homo sapiens Human PF07714 PF14604 7.9 IC50 ChEMBL
Q15746 MYLK Homo sapiens Human PF16620 PF00041 PF07679 PF00069 7.8 Ki ChEMBL;BindingDB
P80192 MAP3K9 Homo sapiens Human PF07714 PF14604 7.7 IC50 ChEMBL
P11802 CDK4 Homo sapiens Human PF00069 7.5 IC50 ChEMBL
P24385 CCND1 Homo sapiens Human PF02984 PF00134 7.5 IC50 ChEMBL
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 7.4 IC50 ChEMBL
Q02779 MAP3K10 Homo sapiens Human PF07714 PF14604 7.3 IC50 ChEMBL
P06213 INSR Homo sapiens Human PF00757 PF17870 PF07714 PF01030 6.7 IC50 BindingDB
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.6 IC50 ChEMBL
P05129 PRKCG Homo sapiens Human PF00130 PF00168 PF00069 PF00433 6.6 IC50 ChEMBL
P05771 PRKCB Homo sapiens Human PF00130 PF00168 PF00069 PF00433 6.6 IC50 ChEMBL
P17252 PRKCA Homo sapiens Human PF00130 PF00168 PF00069 PF00433 6.6 IC50 ChEMBL
P24723 PRKCH Homo sapiens Human PF00130 PF00168 PF00069 PF00433 6.6 IC50 ChEMBL
P41743 PRKCI Homo sapiens Human PF00130 PF00564 PF00069 PF00433 6.6 IC50 ChEMBL
Q02156 PRKCE Homo sapiens Human PF00130 PF00168 PF00069 PF00433 6.6 IC50 ChEMBL
Q04759 PRKCQ Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.6 IC50 ChEMBL
Q05513 PRKCZ Homo sapiens Human PF00130 PF00564 PF00069 PF00433 6.6 IC50 ChEMBL
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.6 IC50 ChEMBL
Q15139 PRKD1 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.6 IC50 ChEMBL
O96020 CCNE2 Homo sapiens Human PF02984 PF00134 6.6 IC50 ChEMBL
P24864 CCNE1 Homo sapiens Human PF02984 PF00134 6.6 IC50 ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.6 IC50 ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.4 IC50 ChEMBL
P08069 IGF1R Homo sapiens Human PF00757 PF07714 PF01030 6.3 IC50 BindingDB