Molecule Details
InChIKeyKOXXIOJJABCMDV-UHFFFAOYSA-N
Compound NameFuro[2,3-d]pyrimidine deriv. 7j
Canonical SMILESCOc1ccc(-c2oc3ncnc(N)c3c2-c2ccc(NC(=O)Nc3ccccc3)cc2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL7.38
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q02763 TEK Homo sapiens Human PF00041 PF10430 PF07714 7.5 IC50 ChEMBL;BindingDB
P35968 KDR Homo sapiens Human PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 7.2 IC50 ChEMBL;BindingDB