Molecule Details
| InChIKey | KORNTPPJEAJQIU-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)-7-prop-2-enyl-6,6a,8,9,10,10a-hexahydro-4H-indolo[4,3-fg]quinoline-9-carboxamide |
| Canonical SMILES | C=CCN1CC(C(=O)N(CCCN(C)C)C(=O)NCC)CC2c3cccc4[nH]cc(c34)CC21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 17 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.55 |
| Source | BindingDB |
2D Structure
Activity Profile
Target Activities (17)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P14416 | DRD2 | Homo sapiens | Human | PF00001 | 9.1 | Ki | BindingDB |
| P35462 | DRD3 | Homo sapiens | Human | PF00001 | 9.1 | Ki | BindingDB |
| P41595 | HTR2B | Homo sapiens | Human | PF00001 | 8.9 | Ki | BindingDB |
| P28223 | HTR2A | Homo sapiens | Human | PF00001 | 8.2 | Ki | BindingDB |
| P28221 | HTR1D | Homo sapiens | Human | PF00001 | 8.1 | Ki | BindingDB |
| P08913 | ADRA2A | Homo sapiens | Human | PF00001 | 7.9 | Ki | BindingDB |
| P08908 | HTR1A | Homo sapiens | Human | PF00001 | 7.7 | Ki | BindingDB |
| P18825 | ADRA2C | Homo sapiens | Human | PF00001 | 7.7 | Ki | BindingDB |
| P21918 | DRD5 | Homo sapiens | Human | PF00001 | 7.7 | Ki | BindingDB |
| P21917 | DRD4 | Homo sapiens | Human | PF00001 | 7.2 | Ki | BindingDB |
| P35368 | ADRA1B | Homo sapiens | Human | PF00001 | 7.2 | Ki | BindingDB |
| P18089 | ADRA2B | Homo sapiens | Human | PF00001 | 7.1 | Ki | BindingDB |
| P25100 | ADRA1D | Homo sapiens | Human | PF00001 | 6.8 | Ki | BindingDB |
| P21728 | DRD1 | Homo sapiens | Human | PF00001 | 6.7 | Ki | BindingDB |
| P35348 | ADRA1A | Homo sapiens | Human | PF00001 | 6.5 | Ki | BindingDB |
| P28222 | HTR1B | Homo sapiens | Human | PF00001 | 6.3 | Ki | BindingDB |
| P28335 | HTR2C | Homo sapiens | Human | PF00001 | 6.2 | Ki | BindingDB |