InChIKey	KORNTPPJEAJQIU-KJXAQDMKSA-N
Compound Name	Cabergoline
Canonical SMILES	C=CCN1C[C@H](C(=O)N(CCCN(C)C)C(=O)NCC)C[C@@H]2c3cccc4[nH]cc(c34)C[C@H]21
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	9.05
Source	ChEMBL;BindingDB

DrugBank ID	DB00248
Drug Name	Cabergoline
CAS Number	81409-90-7
Groups	approved investigational
ATC Codes	N04BC06 G02CB03
Description	Cabergoline, an ergot derivative, is a long-acting dopamine agonist and prolactin inhibitor. It is used to treat hyperprolactinemic disorders and Parkinsonian Syndrome. Cabergoline possesses potent agonist activity on dopamine D2 receptors.

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Categories: Agents that produce hypertension Alkaloids Anti-Dyskinesia Agents Anti-Parkinson Drugs Antidepressive Agents Antineoplastic Agents Central Nervous System Agents Central Nervous System Depressants Cytochrome P-450 CYP3A Inhibitors Cytochrome P-450 CYP3A Substrates Cytochrome P-450 CYP3A4 Inhibitors Cytochrome P-450 CYP3A4 Substrates Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic Index Cytochrome P-450 Enzyme Inhibitors Cytochrome P-450 Substrates Dopamine Agents Dopamine Agonists Ergolines Ergot Alkaloids and Derivatives Ergot-derivative Dopamine Receptor Agonists Genito Urinary System and Sex Hormones Heterocyclic Compounds, Fused-Ring Narrow Therapeutic Index Drugs Nervous System Neurotransmitter Agents P-glycoprotein substrates P-glycoprotein substrates with a Narrow Therapeutic Index Prolactine Inhibitors Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome Serotonin 5-HT1 Receptor Agonists Serotonin 5-HT2 Receptor Agonists Serotonin Agents Serotonin Modulators Serotonin Receptor Agonists

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Cross-references: BindingDB: 50426497 ChEBI: 3286 CHEMBL1201087 ChemSpider: 49452 Drugs Product Database (DPD): 12006 Guide to Pharmacology: 37 IUPHAR: 37 C08187 D00987 PharmGKB: PA448708 PubChem:54746 PubChem:46508571 RxCUI: 47579 Therapeutic Targets Database: DAP000251 Wikipedia: Cabergoline ZINC: ZINC000003800008