Molecule Details
| InChIKey | KONPIFGGWNMOKY-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-(6-ethoxynaphthalen-2-yl)-1-((1-methylpiperidin-4-yl)methyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
| Canonical SMILES | CCOc1ccc2cc(-c3nn(CC4CCN(C)CC4)c4ncnc(N)c34)ccc2c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.1 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q12809 | KCNH2 | Homo sapiens | Human | PF00027 PF00520 PF13426 | 6.4 | IC50 | ChEMBL;BindingDB |
| A0A7S7LIM2 | Cryptosporidium parvum | Pathogen | PF13499 PF00069 | 9.0 | IC50 | BindingDB | |
| Q6S4W0 | CDPK1 | Cryptosporidium parvum | Pathogen | PF13499 PF00069 | 9.0 | IC50 | BindingDB |
| Q8IBS5 | CDPK4 | Plasmodium falciparum (isolate 3D7) | Pathogen | PF13499 PF00069 | 8.0 | IC50 | ChEMBL;BindingDB |