Molecule Details
InChIKeyKOBHCUDVWOTEKO-VKHMYHEASA-N
Compound Namenor-NOHA
Canonical SMILESN=C(NO)NCC[C@H](N)C(=O)O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Homologous
Avg pChEMBL6.82
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB02381
Drug Namenor-NOHA
CAS Number189302-40-7
Groups investigational
ATC Codes nan
DescriptionN-Hydroxy-nor-L-arginine (nor-NOHA) is under investigation in clinical trial NCT02009527 (Arginase Inhibition in Ischemia-reperfusion Injury).

Cross-references: BindingDB: 50008099 ChEBI: 191070 CHEMBL1234777 ChemSpider: 393563 PDB: NNH PubChem:446124 PubChem:46505343 ZINC: ZINC000002244322
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P78540 ARG2 Homo sapiens Human PF00491 7.3 Ki ChEMBL;BindingDB
P05089 ARG1 Homo sapiens Human PF00491 6.3 Kd ChEMBL;BindingDB
DrugBank Target Actions (2)
Target Gene Target Name Action Type
P05089 ARG1 Arginase-1 binder targets
P78540 ARG2 Arginase-2, mitochondrial inhibitor targets