(4M)-N-{(1S)-2-(dimethylamino)-2-oxo-1-[3-(trifluoromethyl)phenyl]ethyl}-4-(1-methyl-1H-pyrazol-5-yl)-4'-(trifluoromethyl)[1,1'-biphenyl]-2-carboxamide

InChIKey	`KNKLXKBJJSPVFJ-VWLOTQADSA-N`
Compound Name	(4M)-N-{(1S)-2-(dimethylamino)-2-oxo-1-[3-(trifluoromethyl)phenyl]ethyl}-4-(1-methyl-1H-pyrazol-5-yl)-4'-(trifluoromethyl)[1,1'-biphenyl]-2-carboxamide
Canonical SMILES	`CN(C)C(=O)[C@@H](NC(=O)c1cc(-c2ccnn2C)ccc1-c1ccc(C(F)(F)F)cc1)c1cccc(C(F)(F)F)c1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	6.34
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
Q29983	MICA	Homo sapiens	Human	PF07654 PF00129	6.5	IC50	ChEMBL
P26718	KLRK1	Homo sapiens	Human	PF00059	6.3	IC50	ChEMBL
Q5VY80	RAET1L	Homo sapiens	Human	PF00129	6.2	IC50	ChEMBL