N-methyl-3-[2-[[(3S)-piperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1H-pyrrolo[2,3-b]pyridine-6-carboxamide

InChIKey	`KNKBXFUDTNASDX-JTQLQIEISA-N`
Compound Name	N-methyl-3-[2-[[(3S)-piperidin-3-yl]amino]-5-(trifluoromethyl)pyrimidin-4-yl]-1H-pyrrolo[2,3-b]pyridine-6-carboxamide
Canonical SMILES	`CNC(=O)c1ccc2c(-c3nc(N[C@H]4CCCNC4)ncc3C(F)(F)F)c[nH]c2n1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	6
Pfam Stratification	Cross-Family
Avg pChEMBL	6.7
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O60563	CCNT1	Homo sapiens	Human	PF00134 PF21797	6.7	IC50	ChEMBL
O75909	CCNK	Homo sapiens	Human	PF00134 PF21797	6.7	IC50	ChEMBL
P24864	CCNE1	Homo sapiens	Human	PF02984 PF00134	6.7	IC50	ChEMBL
P24941	CDK2	Homo sapiens	Human	PF00069	6.7	IC50	ChEMBL
P50750	CDK9	Homo sapiens	Human	PF00069	6.7	IC50	ChEMBL
Q9NYV4	CDK12	Homo sapiens	Human	PF00069	6.7	IC50	ChEMBL