Molecule Details
| InChIKey | KNIHFXMFUCCLGH-UHFFFAOYSA-N |
|---|---|
| Compound Name | (2-Bromo-4,5-dimethoxyphenyl)(6,7-dimethoxy-1-isoquinolinyl)methanone |
| Canonical SMILES | COc1cc(Br)c(C(=O)c2nccc3cc(OC)c(OC)cc23)cc1OC |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.39 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q96LD8 | SENP8 | Homo sapiens | Human | PF02902 | 6.4 | IC50 | BindingDB |
| P42574 | CASP3 | Homo sapiens | Human | PF00656 | 6.4 | IC50 | BindingDB |
| P63279 | UBE2I | Homo sapiens | Human | PF00179 | 6.4 | IC50 | BindingDB |
| Q9UBE0 | SAE1 | Homo sapiens | Human | PF00899 | 6.4 | IC50 | ChEMBL |
| Q9UBT2 | UBA2 | Homo sapiens | Human | PF00899 PF14732 PF16195 | 6.4 | IC50 | ChEMBL |