Molecule Details
| InChIKey | KLKHVLINJXRNBG-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-(Biphenyl-3-yl)-5-(piperidin-4-yl)isoxazol-3-ol |
| Canonical SMILES | Oc1noc(C2CCNCC2)c1-c1cccc(-c2ccccc2)c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.56 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P28472 | GABRB3 | Homo sapiens | Human | PF02931 PF02932 | 8.0 | Ki | ChEMBL |
| P14867 | GABRA1 | Homo sapiens | Human | PF02931 PF02932 | 7.6 | IC50 | ChEMBL;BindingDB |
| P18507 | GABRG2 | Homo sapiens | Human | PF02931 PF02932 | 7.6 | IC50 | ChEMBL |
| P47870 | GABRB2 | Homo sapiens | Human | PF02931 PF02932 | 7.1 | IC50 | ChEMBL |