4-[3-(3-chloroanilino)-5-(4-hydroxyphenyl)-1H-pyrazol-4-yl]phenol

InChIKey	`KJVWCDAPVMWKLJ-UHFFFAOYSA-N`
Compound Name	4-[3-(3-chloroanilino)-5-(4-hydroxyphenyl)-1H-pyrazol-4-yl]phenol
Canonical SMILES	`Oc1ccc(-c2n[nH]c(Nc3cccc(Cl)c3)c2-c2ccc(O)cc2)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	20
Pfam Stratification	Cross-Family
Avg pChEMBL	6.36
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O75116	ROCK2	Homo sapiens	Human	PF25346 PF00069 PF08912	7.2	Ki	ChEMBL
Q9UEE5	STK17A	Homo sapiens	Human	PF00069	7.2	Ki	ChEMBL
Q13464	ROCK1	Homo sapiens	Human	PF25346 PF00069 PF08912	6.7	Ki	ChEMBL
P23443	RPS6KB1	Homo sapiens	Human	PF00069 PF00433	6.6	Ki	ChEMBL
P07949	RET	Homo sapiens	Human	PF00028 PF07714 PF17756 PF17812 PF17813 PF22540	6.5	Ki	ChEMBL
P51812	RPS6KA3	Homo sapiens	Human	PF00069 PF00433	6.5	Ki	ChEMBL
P51817	PRKX	Homo sapiens	Human	PF00069	6.4	Ki	ChEMBL
Q9Y4K4	MAP4K5	Homo sapiens	Human	PF00780 PF00069	6.4	Ki	ChEMBL
Q13627	DYRK1A	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
Q16513	PKN2	Homo sapiens	Human	PF02185 PF00069 PF00433	6.3	Ki	ChEMBL
Q9HAZ1	CLK4	Homo sapiens	Human	PF00069	6.3	Ki	ChEMBL
P16591	FER	Homo sapiens	Human	PF00611 PF07714 PF00017	6.2	Ki	ChEMBL
Q14680	MELK	Homo sapiens	Human	PF02149 PF00069 PF21594	6.2	Ki	ChEMBL
Q9HBY8	SGK2	Homo sapiens	Human	PF00069 PF00433	6.2	Ki	ChEMBL
P30530	AXL	Homo sapiens	Human	PF00041 PF13927 PF07714	6.1	Ki	ChEMBL
P42679	MATK	Homo sapiens	Human	PF07714 PF00017 PF00018	6.1	Ki	ChEMBL
O43781	DYRK3	Homo sapiens	Human	PF00069	6.0	Ki	ChEMBL
O95819	MAP4K4	Homo sapiens	Human	PF00780 PF00069	6.0	Ki	ChEMBL
P43405	SYK	Homo sapiens	Human	PF07714 PF00017	6.0	Ki	ChEMBL
Q9H3Y6	SRMS	Homo sapiens	Human	PF07714 PF00017	6.0	Ki	ChEMBL