Molecule Details
| InChIKey | KJVHTJKPBZOBPJ-UHFFFAOYSA-N |
|---|---|
| Compound Name | 2-(4-methoxyphenylthio)-N-(5-methyl-1H-pyrazol-3-yl)quinazolin-4-amine |
| Canonical SMILES | COc1ccc(Sc2nc(Nc3cc(C)[nH]n3)c3ccccc3n2)cc1 |
| Clinical Status | Clinical Multi-Target |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.31 |
| Source | ChEMBL;BindingDB;TTD_MultiTarget |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O14965 | AURKA | Homo sapiens | Human | PF00069 | 8.1 | Ki | ChEMBL;BindingDB |
| O75716 | STK16 | Homo sapiens | Human | PF00069 | 8.1 | pIC50 | TTD_MultiTarget |
| P49841 | GSK3B | Homo sapiens | Human | PF00069 | 6.9 | Ki | ChEMBL;BindingDB |
| Q96GD4 | AURKB | Homo sapiens | Human | PF00069 | 6.2 | Ki | ChEMBL;BindingDB |