Molecule Details
InChIKeyKJOQLFMPAVEWLJ-UHFFFAOYSA-N
Compound Name1-[2-hydroxy-4-(2-hydroxyphenyl)-4-methyl-2-(trifluoromethyl)pentyl]-1H-quinolin-4-one
Canonical SMILESCC(C)(CC(O)(Cn1ccc(=O)c2ccccc21)C(F)(F)F)c1ccccc1O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL6.94
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
P04150 NR3C1 Homo sapiens Human PF02155 PF00104 PF00105 8.2 IC50 ChEMBL;BindingDB
P08235 NR3C2 Homo sapiens Human PF00104 PF00105 6.3 IC50 ChEMBL;BindingDB
P06401 PGR Homo sapiens Human PF00104 PF02161 PF00105 6.3 IC50 ChEMBL;BindingDB