Molecule Details
InChIKeyKJAAPZIFCQQQKX-NDEPHWFRSA-N
Canonical SMILESCC1=C(c2cccc(O)c2)[C@H](c2ccc(OCCN3CC(CF)C3)cc2)Oc2ccc(O)cc21
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL8.24
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB14934
Drug NameGDC-0927
CAS Number2100830-77-9
Groups investigational
ATC Codes nan
DescriptionGDC-0927 is under investigation in clinical trial NCT02316509 (A Study of GDC-0927 in Postmenopausal Women With Locally Advanced or Metastatic Estrogen Receptor Positive Breast Cancer).

Cross-references: ChemSpider: 64835178 PDB: OGJ
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
P03372 ESR1 Homo sapiens Human PF12743 PF00104 PF02159 PF00105 10.1 IC50 ChEMBL;BindingDB
Q01959 SLC6A3 Homo sapiens Human PF00209 6.4 IC50 ChEMBL;BindingDB