Molecule Details
| InChIKey | KIUXCHKRJQPHFK-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[(4-chlorophenyl)methyl]-4-(4-methoxyphenyl)pyrimidin-2-amine |
| Canonical SMILES | COc1ccc(-c2ccnc(NCc3ccc(Cl)cc3)n2)cc1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 4 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.35 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (4)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P49759 | CLK1 | Homo sapiens | Human | PF00069 | 6.6 | IC50 | ChEMBL;BindingDB |
| Q9HAZ1 | CLK4 | Homo sapiens | Human | PF00069 | 6.5 | IC50 | ChEMBL;BindingDB |
| Q13627 | DYRK1A | Homo sapiens | Human | PF00069 | 6.2 | IC50 | ChEMBL;BindingDB |
| Q9Y463 | DYRK1B | Homo sapiens | Human | PF00069 | 6.1 | IC50 | ChEMBL;BindingDB |