Molecule Details
| InChIKey | KIEFRRZUZZNWHT-UHFFFAOYSA-N |
|---|---|
| Compound Name | 9-(2-Methyl-4-pyridinyl)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one |
| Canonical SMILES | Cc1cc(-c2ccc3c(c2)Nc2ccccc2NC3=O)ccn1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 6 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.53 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (6)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q9HAZ1 | CLK4 | Homo sapiens | Human | PF00069 | 7.2 | Ki | ChEMBL |
| O00311 | CDC7 | Homo sapiens | Human | PF00069 | 6.9 | Ki | ChEMBL |
| Q9HBH9 | MKNK2 | Homo sapiens | Human | PF00069 | 6.5 | Ki | ChEMBL |
| P24941 | CDK2 | Homo sapiens | Human | PF00069 | 6.3 | Ki | ChEMBL |
| P49841 | GSK3B | Homo sapiens | Human | PF00069 | 6.2 | Ki | ChEMBL |
| O95819 | MAP4K4 | Homo sapiens | Human | PF00780 PF00069 | 6.1 | Ki | ChEMBL |