Molecule Details
InChIKeyKIAKJNRDKPGTQR-OAGGEKHMSA-N
Compound NameUS11111247, Example 17
Canonical SMILESCOC(=O)N1C[C@@H](C)N(c2ncc3[nH]nc(-c4ccc(N5CCN[C@H](C)C5)nc4)c3n2)[C@@H](C)C1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL7.57
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
Q04771 ACVR1 Homo sapiens Human PF01064 PF07714 PF08515 8.3 IC50 ChEMBL;BindingDB
P37023 ACVRL1 Homo sapiens Human PF07714 PF08515 8.2 IC50 ChEMBL;BindingDB
P81172 HAMP Homo sapiens Human PF06446 8.1 IC50 ChEMBL;BindingDB
P36897 TGFBR1 Homo sapiens Human PF01064 PF00069 PF08515 7.6 IC50 ChEMBL;BindingDB
P36894 BMPR1A Homo sapiens Human PF01064 PF07714 PF08515 6.6 IC50 ChEMBL;BindingDB
P11362 FGFR1 Homo sapiens Human PF07679 PF00047 PF07714 6.5 IC50 ChEMBL;BindingDB