InChIKey	KHPKQFYUPIUARC-UHFFFAOYSA-N
Compound Name	Lumiracoxib
Canonical SMILES	Cc1ccc(Nc2c(F)cccc2Cl)c(CC(=O)O)c1
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.52
Source	ChEMBL;BindingDB

DrugBank ID	DB01283
Drug Name	Lumiracoxib
CAS Number	220991-20-8
Groups	approved withdrawn
ATC Codes	M01AH06
Description	Lumiracoxib is a COX-2 selective non-steroidal anti-inflammatory drug (NSAID). On August 11, 2007, Australia's Therapeutic Goods Administration (TGA, the Australian equivalent of the FDA) cancelled the registration of lumiracoxib in Australia due to concerns that it may cause liver failure. New Zeal...

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Categories: Acids, Carbocyclic Agents causing hyperkalemia Agents that produce hypertension Analgesics Analgesics, Non-Narcotic Anti-Inflammatory Agents Anti-Inflammatory Agents, Non-Steroidal Antiinflammatory and Antirheumatic Products Antiinflammatory and Antirheumatic Products, Non-Steroids Antirheumatic Agents COX-2 Inhibitors Cyclooxygenase Inhibitors Cytochrome P-450 CYP1A2 Substrates Cytochrome P-450 CYP2C19 Substrates Cytochrome P-450 CYP2C9 Substrates Cytochrome P-450 Substrates Enzyme Inhibitors Musculo-Skeletal System Nephrotoxic agents Peripheral Nervous System Agents Phenylacetates Selective Cyclooxygenase 2 Inhibitors (NSAIDs) Sensory System Agents UGT1A9 Substrates

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Cross-references: BindingDB: 50207446 ChEBI: 73044 CHEMBL404108 ChemSpider: 133236 D03714 PDB: LUR PharmGKB: PA164769031 PubChem:151166 PubChem:46506378 Therapeutic Targets Database: DAP000970 Wikipedia: Lumiracoxib ZINC: ZINC000000007563