Molecule Details
InChIKeyKGOHHLONXFWMRE-SFHVURJKSA-N
Compound Name(4R)-3-[5-[2-(4-butylphenyl)ethynyl]thiophen-2-yl]sulfonyl-N-hydroxy-1,3-thiazolidine-4-carboxamide
Canonical SMILESCCCCc1ccc(C#Cc2ccc(S(=O)(=O)N3CSC[C@H]3C(=O)NO)s2)cc1
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL7.41
SourceChEMBL;BindingDB;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P08253 MMP2 Homo sapiens Human PF00040 PF00045 PF00413 8.6 pIC50 TTD_MultiTarget
P14780 MMP9 Homo sapiens Human PF00040 PF00045 PF00413 7.7 IC50 ChEMBL;BindingDB
P08254 MMP3 Homo sapiens Human PF00045 PF00413 PF01471 7.4 IC50 ChEMBL;BindingDB
Q9NPA2 MMP25 Homo sapiens Human PF00045 PF00413 PF01471 6.8 IC50 ChEMBL;BindingDB
P22894 MMP8 Homo sapiens Human PF00045 PF00413 PF01471 6.3 IC50 ChEMBL;BindingDB
P18843 nadE Escherichia coli (strain K12) Pathogen PF02540 7.7 pIC50 TTD_MultiTarget