Molecule Details
| InChIKey | KEEBLYWBELVGPQ-UHFFFAOYSA-N |
|---|---|
| Compound Name | Bms-986141 |
| Canonical SMILES | COc1cc(OCc2csc(-c3ccc(C(=O)N(C)C)cc3)n2)c2cc(-c3cn4nc(OC)sc4n3)oc2c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.91 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB14942 |
|---|---|
| Drug Name | BMS-986141 |
| CAS Number | 1478711-48-6 |
| Groups | investigational |
| ATC Codes | nan |
| Description | BMS-986141 is under investigation in clinical trial NCT02985632 (A Study to Evaluate the Pharmacokinetics of BMS-986141 in Participants With Hepatic Impairment Compared to Healthy Participants). |
Categories: Acids, Carbocyclic Amides Benzene Derivatives Benzoates Sulfur Compounds Thiazoles
Cross-references: BindingDB: 176003 CHEMBL3716552 ChemSpider: 58960890 ZINC: ZINC000205663568
Target Activities (3)
DrugBank Target Actions (1)
| Target | Gene | Target Name | Action | Type |
|---|---|---|---|---|
| Q96IZ0 | Q96IZ0 | PRKC apoptosis WT1 regulator protein | antagonist | targets |