4-amino-3-(3,5-dimethyl-1-benzofuran-2-yl)-2-(1-prop-2-enoylpiperidin-3-yl)-6H-pyrazolo[3,4-d]pyridazin-7-one

InChIKey	`KEAWMUNHKYSQEN-UHFFFAOYSA-N`
Compound Name	4-amino-3-(3,5-dimethyl-1-benzofuran-2-yl)-2-(1-prop-2-enoylpiperidin-3-yl)-6H-pyrazolo[3,4-d]pyridazin-7-one
Canonical SMILES	`C=CC(=O)N1CCCC(n2nc3c(=O)[nH]nc(N)c3c2-c2oc3ccc(C)cc3c2C)C1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Homologous
Avg pChEMBL	7.54
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P21802	FGFR2	Homo sapiens	Human	PF07679 PF13927 PF07714	7.8	IC50	ChEMBL
P22455	FGFR4	Homo sapiens	Human	PF07679 PF13927 PF07714	7.5	IC50	ChEMBL
P22607	FGFR3	Homo sapiens	Human	PF21165 PF07679 PF13927 PF07714	7.3	IC50	ChEMBL