Molecule Details
InChIKeyKDMADGZAPDHVHE-UHFFFAOYSA-N
Compound NameJNK3 inhibitor-1
Canonical SMILESCc1nc2c(cnn2-c2csc(C(=O)NC3COC3)c2)cc1Nc1c(F)cccc1Cl
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)6
Pfam Stratification Cross-Family
Avg pChEMBL7.07
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (6)
Target Gene Organism Category Pfam pChEMBL Type Source
P53779 MAPK10 Homo sapiens Human PF00069 8.3 IC50 ChEMBL;BindingDB
P45984 MAPK9 Homo sapiens Human PF00069 7.1 IC50 ChEMBL;BindingDB
P49674 CSNK1E Homo sapiens Human PF00069 7.0 IC50 ChEMBL;BindingDB
Q16539 MAPK14 Homo sapiens Human PF00069 7.0 IC50 ChEMBL;BindingDB
Q08345 DDR1 Homo sapiens Human PF21114 PF00754 PF07714 6.6 IC50 ChEMBL;BindingDB
P45983 MAPK8 Homo sapiens Human PF00069 6.4 IC50 ChEMBL;BindingDB