Molecule Details
InChIKeyKDJGCVHPUMHUOL-UHFFFAOYSA-N
Compound Name1-Hydroxy-9-(4-hydroxy-3-methoxyphenyl)-5,11-dihydrobenzo[b][1,4]benzodiazepin-6-one
Canonical SMILESCOc1cc(-c2ccc3c(c2)Nc2c(O)cccc2NC3=O)ccc1O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)11
Pfam Stratification Cross-Family
Avg pChEMBL6.63
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (11)
Target Gene Organism Category Pfam pChEMBL Type Source
Q00535 CDK5 Homo sapiens Human PF00069 7.8 Ki ChEMBL
Q04771 ACVR1 Homo sapiens Human PF01064 PF07714 PF08515 7.8 Ki ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 6.8 Ki ChEMBL
O14757 CHEK1 Homo sapiens Human PF00069 6.7 Ki ChEMBL;BindingDB
Q06418 TYRO3 Homo sapiens Human PF00041 PF07679 PF07714 6.6 Ki ChEMBL
Q9Y463 DYRK1B Homo sapiens Human PF00069 6.5 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P29376 LTK Homo sapiens Human PF12810 PF07714 6.2 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.1 Ki ChEMBL
P00519 ABL1 Homo sapiens Human PF08919 PF07714 PF00017 PF00018 6.1 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.0 Ki ChEMBL