Molecule Details
| InChIKey | KCLZJAVIQDVQCK-UHFFFAOYSA-N |
|---|---|
| Compound Name | Tert-butyl 5-[[3,4-dioxo-2-[(4-sulfamoylphenyl)methylamino]cyclobuten-1-yl]amino]indazole-1-carboxylate |
| Canonical SMILES | CC(C)(C)OC(=O)n1ncc2cc(Nc3c(NCc4ccc(S(N)(=O)=O)cc4)c(=O)c3=O)ccc21 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.42 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P51817 | PRKX | Homo sapiens | Human | PF00069 | 7.0 | Ki | ChEMBL |
| O75116 | ROCK2 | Homo sapiens | Human | PF25346 PF00069 PF08912 | 6.7 | Ki | ChEMBL |
| Q9HAZ1 | CLK4 | Homo sapiens | Human | PF00069 | 6.3 | Ki | ChEMBL |
| Q13464 | ROCK1 | Homo sapiens | Human | PF25346 PF00069 PF08912 | 6.1 | Ki | ChEMBL |
| O00418 | EEF2K | Homo sapiens | Human | PF02816 | 6.0 | Ki | ChEMBL |