Molecule Details
InChIKeyKCKXYZOBGBJZEG-UHFFFAOYSA-N
Compound Name5-[1-benzyl-5-(4-fluorophenyl)triazol-4-yl]-1H-indazol-3-amine
Canonical SMILESNc1n[nH]c2ccc(-c3nnn(Cc4ccccc4)c3-c3ccc(F)cc3)cc12
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)36
Pfam Stratification Cross-Family
Avg pChEMBL6.76
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (36)
Target Gene Organism Category Pfam pChEMBL Type Source
O00311 CDC7 Homo sapiens Human PF00069 8.8 Ki ChEMBL;BindingDB
Q9HAZ1 CLK4 Homo sapiens Human PF00069 8.2 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 8.0 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 7.9 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 7.8 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 7.4 Ki ChEMBL
P17612 PRKACA Homo sapiens Human PF00069 7.3 Ki ChEMBL
P28482 MAPK1 Homo sapiens Human PF00069 7.3 Ki ChEMBL
P51817 PRKX Homo sapiens Human PF00069 7.3 Ki ChEMBL
Q5VT25 CDC42BPA Homo sapiens Human PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 PF00433 7.3 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 7.1 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 7.0 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.9 Ki ChEMBL
O43293 DAPK3 Homo sapiens Human PF00069 6.8 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.6 Ki ChEMBL
Q8N4C8 MINK1 Homo sapiens Human PF00780 PF00069 6.6 Ki ChEMBL
O00444 PLK4 Homo sapiens Human PF00069 PF18190 PF18409 6.5 Ki ChEMBL
P52333 JAK3 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.5 Ki ChEMBL
Q13976 PRKG1 Homo sapiens Human PF00027 PF16808 PF00069 6.5 Ki ChEMBL
Q9UEE5 STK17A Homo sapiens Human PF00069 6.5 Ki ChEMBL
O60674 JAK2 Homo sapiens Human PF18379 PF18377 PF17887 PF07714 PF21990 6.4 Ki ChEMBL
P23443 RPS6KB1 Homo sapiens Human PF00069 PF00433 6.4 Ki ChEMBL
P68400 CSNK2A1 Homo sapiens Human PF00069 6.4 Ki ChEMBL
Q9HBH9 MKNK2 Homo sapiens Human PF00069 6.4 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P50750 CDK9 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.3 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.2 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 6.2 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
P27448 MARK3 Homo sapiens Human PF02149 PF00069 PF00627 6.1 Ki ChEMBL
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 6.1 Ki ChEMBL
O15264 MAPK13 Homo sapiens Human PF00069 6.0 Ki ChEMBL
P04629 NTRK1 Homo sapiens Human PF13855 PF16920 PF07714 PF18613 6.0 Ki ChEMBL
P53778 MAPK12 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q14680 MELK Homo sapiens Human PF02149 PF00069 PF21594 6.0 Ki ChEMBL