Molecule Details
| InChIKey | KCCWVRNMXATDGV-UHFFFAOYSA-N |
|---|---|
| Compound Name | 1-[4-(3-Amino-6-methyl-[1,2]oxazolo[3,4-b]pyridin-4-yl)phenyl]-3-(3-chlorophenyl)urea |
| Canonical SMILES | Cc1cc(-c2ccc(NC(=O)Nc3cccc(Cl)c3)cc2)c2c(N)onc2n1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 7.77 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P36888 | FLT3 | Homo sapiens | Human | PF00047 PF07714 | 8.3 | IC50 | ChEMBL;BindingDB |
| P35968 | KDR | Homo sapiens | Human | PF07679 PF00047 PF13895 PF22971 PF07714 PF21339 PF17988 PF22854 | 7.6 | IC50 | ChEMBL;BindingDB |
| P09619 | PDGFRB | Homo sapiens | Human | PF00047 PF13927 PF25305 PF07714 | 7.4 | IC50 | ChEMBL;BindingDB |