Molecule Details
InChIKeyKCAJXIDMCNPGHZ-UHFFFAOYSA-N
Compound NamePH 797804
Canonical SMILESCNC(=O)c1ccc(C)c(-n2c(C)cc(OCc3ccc(F)cc3F)c(Br)c2=O)c1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)3
Pfam Stratification Homologous
Avg pChEMBL7.37
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB07941
Drug NamePH-797804
CAS Number586379-66-0
Groups investigational
ATC Codes nan
DescriptionPH-797804 has been investigated for the treatment of Osteoarthritis.
Categories: Acids, Carbocyclic Amides Benzene Derivatives Benzoates Pyridines p38 Mitogen-Activated Protein Kinases, antagonists & inhibitors
Cross-references: BindingDB: 50314073 ChEBI: 82715 CHEMBL1088751 ChemSpider: 10796940 PDB: I45 PubChem:22049997 PubChem:99444412 ZINC: ZINC000013980453
Target Activities (3)
Target Gene Organism Category Pfam pChEMBL Type Source
Q16539 MAPK14 Homo sapiens Human PF00069 8.5 IC50 ChEMBL;BindingDB
Q15759 MAPK11 Homo sapiens Human PF00069 7.4 Ki ChEMBL;BindingDB
Q7RTN6 STRADA Homo sapiens Human PF00069 6.2 Kd ChEMBL
DrugBank Target Actions (1)
Target Gene Target Name Action Type
Q16539 MAPK14 Mitogen-activated protein kinase 14 binder targets