Molecule Details
| InChIKey | KBRJIBFRLFVYJL-UHFFFAOYSA-N |
|---|---|
| Compound Name | 3-(1-Cyclohexylethylamino)-4-(pyridin-4-ylamino)cyclobut-3-ene-1,2-dione |
| Canonical SMILES | CC(Nc1c(Nc2ccncc2)c(=O)c1=O)C1CCCCC1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 6.4 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| O43293 | DAPK3 | Homo sapiens | Human | PF00069 | 6.7 | Ki | ChEMBL |
| P53350 | PLK1 | Homo sapiens | Human | PF00069 PF00659 | 6.5 | Ki | ChEMBL |
| O75116 | ROCK2 | Homo sapiens | Human | PF25346 PF00069 PF08912 | 6.4 | Ki | ChEMBL |
| Q13464 | ROCK1 | Homo sapiens | Human | PF25346 PF00069 PF08912 | 6.4 | Ki | ChEMBL |
| Q9H4B4 | PLK3 | Homo sapiens | Human | PF00069 PF00659 | 6.0 | Ki | ChEMBL |