Molecule Details
InChIKeyKAZSKMJFUPEHHW-DHZHZOJOSA-N
Canonical SMILESC=CC(C)(C)c1cc(/C=C/C(=O)c2ccc(O)cc2)c(OC)cc1O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL6.54
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB19281
Drug NameLicochalcone A
CAS Number58749-22-7
Groups experimental
ATC Codes nan
Descriptionnan
Categories: Benzopyrans Chromones Fabaceae Flavonoids Heterocyclic Compounds, Fused-Ring Ketones Propiophenones Pyrans
Cross-references: BindingDB: 50068270 ChEBI: 174541 CHEMBL139702 ChemSpider: 4477422 Wikipedia: Licochalcone_A ZINC: ZINC000003873123
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9UNQ0 ABCG2 Homo sapiens Human PF01061 PF19055 PF00005 7.1 IC50 ChEMBL;BindingDB
P22309 UGT1A1 Homo sapiens Human PF00201 6.0 IC50 ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
P18031 PTPN1 Tyrosine-protein phosphatase non-receptor type 1 inhibitor targets