Molecule Details
InChIKeyKAKFXRYHYUPXSU-UHFFFAOYSA-N
Compound Name4-methoxy-N-(3-phenyl-1H-pyrrolo[2,3-b]pyridin-5-yl)benzamide
Canonical SMILESCOc1ccc(C(=O)Nc2cnc3[nH]cc(-c4ccccc4)c3c2)cc1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)16
Pfam Stratification Cross-Family
Avg pChEMBL6.34
SourceChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (16)
Target Gene Organism Category Pfam pChEMBL Type Source
Q16288 NTRK3 Homo sapiens Human PF07679 PF00047 PF13855 PF16920 PF01462 PF07714 7.1 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 6.8 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 6.7 Ki ChEMBL
Q9HAZ1 CLK4 Homo sapiens Human PF00069 6.7 Ki ChEMBL
Q13188 STK3 Homo sapiens Human PF11629 PF00069 6.5 Ki ChEMBL
P30530 AXL Homo sapiens Human PF00041 PF13927 PF07714 6.4 Ki ChEMBL
Q9Y4K4 MAP4K5 Homo sapiens Human PF00780 PF00069 6.3 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 6.2 Ki ChEMBL
Q9HCP0 CSNK1G1 Homo sapiens Human PF12605 PF00069 6.2 Ki ChEMBL
P51957 NEK4 Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q13555 CAMK2G Homo sapiens Human PF08332 PF00069 6.1 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.1 Ki ChEMBL
Q13882 PTK6 Homo sapiens Human PF07714 PF00017 PF00018 6.1 Ki ChEMBL
Q8N4C8 MINK1 Homo sapiens Human PF00780 PF00069 6.1 Ki ChEMBL
P00533 EGFR Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 6.0 Ki ChEMBL
P51451 BLK Homo sapiens Human PF07714 PF00017 PF00018 6.0 Ki ChEMBL