Molecule Details
InChIKeyKAJIDAUQCMSGGN-XQASTXFUSA-N
Compound Name5-Vinyl-3-pyridinecarbonitrile, 19
Canonical SMILESCc1c(Nc2c(C#N)cncc2/C=C/CCN2CCC[C@@H](N)C2)ccc2[nH]ccc12
Clinical Status Clinical Multi-Target
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL7.21
SourceChEMBL;BindingDB;TTD_MultiTarget
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
Q04759 PRKCQ Homo sapiens Human PF00130 PF21494 PF00069 PF00433 8.7 IC50 ChEMBL;BindingDB
Q02156 PRKCE Homo sapiens Human PF00130 PF00168 PF00069 PF00433 7.8 IC50 ChEMBL
P18505 GABRB1 Homo sapiens Human PF02931 PF02932 7.6 pIC50 TTD_MultiTarget
Q05655 PRKCD Homo sapiens Human PF00130 PF21494 PF00069 PF00433 7.6 IC50 ChEMBL;BindingDB
P24723 PRKCH Homo sapiens Human PF00130 PF00168 PF00069 PF00433 6.5 IC50 ChEMBL
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 6.2 IC50 ChEMBL
O14920 IKBKB Homo sapiens Human PF18397 PF12179 PF00069 6.0 IC50 ChEMBL
O96017 CHEK2 Homo sapiens Human PF00498 PF00069 Clinical TTD_MultiTarget TTD_MultiTarget