Molecule Details
InChIKeyKAGWQDFFFLWBFD-ZDUSSCGKSA-N
Compound Name(2S)-2-[[3-(3-chlorophenyl)imidazo[1,2-b]pyridazin-6-yl]amino]butan-1-ol
Canonical SMILESCC[C@@H](CO)Nc1ccc2ncc(-c3cccc(Cl)c3)n2n1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)8
Pfam Stratification Cross-Family
Avg pChEMBL6.82
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (8)
Target Gene Organism Category Pfam pChEMBL Type Source
Q92630 DYRK2 Homo sapiens Human PF00069 7.3 IC50 ChEMBL;BindingDB
Q9Y463 DYRK1B Homo sapiens Human PF00069 7.3 IC50 ChEMBL;BindingDB
Q13627 DYRK1A Homo sapiens Human PF00069 7.1 IC50 ChEMBL;BindingDB
O43781 DYRK3 Homo sapiens Human PF00069 7.1 IC50 ChEMBL;BindingDB
O60563 CCNT1 Homo sapiens Human PF00134 PF21797 6.7 IC50 ChEMBL;BindingDB
P50750 CDK9 Homo sapiens Human PF00069 6.7 IC50 ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.2 IC50 ChEMBL
Q15078 CDK5R1 Homo sapiens Human PF03261 6.2 IC50 ChEMBL;BindingDB