Molecule Details
| InChIKey | JYIUNVOCEFIUIU-GHMZBOCLSA-N |
|---|---|
| Canonical SMILES | C=CC(=O)N[C@@H]1CN(c2nc(Nc3cn(C)nc3OC)c3ncn(C)c3n2)C[C@H]1F |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Homologous |
| Avg pChEMBL | 8.16 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB16228 |
|---|---|
| Drug Name | Mavelertinib |
| CAS Number | 1776112-90-3 |
| Groups | investigational |
| ATC Codes | nan |
| Description | Mavelertinib is under investigation in clinical trial NCT02349633 (Study for Patients With NSCLC EGFR Mutations (Del 19 or L858R +/- T790M)). |
Cross-references: BindingDB: 50450870 CHEMBL3989970 ChemSpider: 49070873 ZINC: ZINC000231225813