N-(2-aminophenyl)-2-[[6-[(4-ethylpiperazin-1-yl)methyl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide

InChIKey	`JXYHYYBXKLTNGG-UHFFFAOYSA-N`
Compound Name	N-(2-aminophenyl)-2-[[6-[(4-ethylpiperazin-1-yl)methyl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide
Canonical SMILES	`CCN1CCN(Cc2cc(Nc3ncc(C(=O)Nc4ccccc4N)s3)nc(C)n2)CC1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	3
Pfam Stratification	Cross-Family
Avg pChEMBL	7.39
Source	BindingDB;ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P00519	ABL1	Homo sapiens	Human	PF08919 PF07714 PF00017 PF00018	7.7	IC50	ChEMBL
P11274	BCR	Homo sapiens	Human	PF09036 PF00168 PF19057 PF00620 PF00621	7.7	IC50	ChEMBL
Q13547	HDAC1	Homo sapiens	Human	PF00850	6.8	IC50	ChEMBL;BindingDB