Molecule Details
| InChIKey | JXRHFSZNVUPMJD-UHFFFAOYSA-N |
|---|---|
| Compound Name | 4-amino-N-(4-oxo-2-piperazin-1-yl-3H-quinazolin-6-yl)butanamide |
| Canonical SMILES | NCCCC(=O)Nc1ccc2nc(N3CCNCC3)[nH]c(=O)c2c1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 3 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 8.19 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (3)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P05106 | ITGB3 | Homo sapiens | Human | PF07974 PF23105 PF18372 PF08725 PF07965 PF00362 PF17205 | 8.3 | IC50 | ChEMBL |
| P08514 | ITGA2B | Homo sapiens | Human | PF01839 PF08441 PF20805 PF20806 PF00357 | 8.3 | IC50 | ChEMBL |
| P17301 | ITGA2 | Homo sapiens | Human | PF01839 PF20805 PF20806 PF00092 | 8.0 | IC50 | BindingDB |