5-(1-benzyl-5-cyclopropyltriazol-4-yl)-1H-indazole

InChIKey	`JXMYIDZREHNPDO-UHFFFAOYSA-N`
Compound Name	5-(1-benzyl-5-cyclopropyltriazol-4-yl)-1H-indazole
Canonical SMILES	`c1ccc(Cn2nnc(-c3ccc4[nH]ncc4c3)c2C2CC2)cc1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	19
Pfam Stratification	Cross-Family
Avg pChEMBL	6.94
Source	ChEMBL

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O75116	ROCK2	Homo sapiens	Human	PF25346 PF00069 PF08912	8.6	Ki	ChEMBL
P49840	GSK3A	Homo sapiens	Human	PF00069	7.8	Ki	ChEMBL
Q13464	ROCK1	Homo sapiens	Human	PF25346 PF00069 PF08912	7.7	Ki	ChEMBL
O43293	DAPK3	Homo sapiens	Human	PF00069	7.5	Ki	ChEMBL
P24941	CDK2	Homo sapiens	Human	PF00069	7.5	Ki	ChEMBL
P06493	CDK1	Homo sapiens	Human	PF00069	7.4	Ki	ChEMBL
O14965	AURKA	Homo sapiens	Human	PF00069	7.2	Ki	ChEMBL
Q13627	DYRK1A	Homo sapiens	Human	PF00069	7.2	Ki	ChEMBL
P28482	MAPK1	Homo sapiens	Human	PF00069	6.9	Ki	ChEMBL
Q96GD4	AURKB	Homo sapiens	Human	PF00069	6.7	Ki	ChEMBL
P51812	RPS6KA3	Homo sapiens	Human	PF00069 PF00433	6.6	Ki	ChEMBL
Q5VT25	CDC42BPA	Homo sapiens	Human	PF00130 PF00780 PF08826 PF15796 PF25346 PF00069 PF00433	6.6	Ki	ChEMBL
P17612	PRKACA	Homo sapiens	Human	PF00069	6.5	Ki	ChEMBL
Q00535	CDK5	Homo sapiens	Human	PF00069	6.5	Ki	ChEMBL
Q05655	PRKCD	Homo sapiens	Human	PF00130 PF21494 PF00069 PF00433	6.5	Ki	ChEMBL
P27448	MARK3	Homo sapiens	Human	PF02149 PF00069 PF00627	6.3	Ki	ChEMBL
O60674	JAK2	Homo sapiens	Human	PF18379 PF18377 PF17887 PF07714 PF21990	6.2	Ki	ChEMBL
Q13131	PRKAA1	Homo sapiens	Human	PF16579 PF21147 PF00069	6.1	Ki	ChEMBL
O15111	CHUK	Homo sapiens	Human	PF18397 PF12179 PF00069	6.0	Ki	ChEMBL