1-[1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[5-methyl-2-(oxan-4-ylamino)pyrimidin-4-yl]pyridin-2-one

InChIKey	`JXKNNYQQOGCFRS-UHFFFAOYSA-N`
Compound Name	1-[1-(4-Chloro-3-fluorophenyl)-2-hydroxyethyl]-4-[5-methyl-2-(oxan-4-ylamino)pyrimidin-4-yl]pyridin-2-one
Canonical SMILES	`Cc1cnc(NC2CCOCC2)nc1-c1ccn(C(CO)c2ccc(Cl)c(F)c2)c(=O)c1`
Clinical Status	Data-mined Candidate
Targets (Human+Pathogen)	4
Pfam Stratification	Cross-Family
Avg pChEMBL	6.78
Source	ChEMBL;BindingDB

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
P28482	MAPK1	Homo sapiens	Human	PF00069	7.3	IC50	ChEMBL;BindingDB
P20248	CCNA2	Homo sapiens	Human	PF02984 PF00134 PF16500	6.9	Kd	ChEMBL
P24941	CDK2	Homo sapiens	Human	PF00069	6.9	Kd	ChEMBL
P27361	MAPK3	Homo sapiens	Human	PF00069	6.1	IC50	ChEMBL