Molecule Details
| InChIKey | JXHFEOAFQXPYIJ-UHFFFAOYSA-N |
|---|---|
| Compound Name | N-[2-[2-[2,5-dimethyl-1-(thiophen-2-ylmethyl)pyrrol-3-yl]-2-oxoethoxy]phenyl]acetamide |
| Canonical SMILES | CC(=O)Nc1ccccc1OCC(=O)c1cc(C)n(Cc2cccs2)c1C |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.34 |
| Source | BindingDB;ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| P07900 | HSP90AA1 | Homo sapiens | Human | PF13589 PF00183 | 7.0 | IC50 | ChEMBL;BindingDB |
| P01375 | TNF | Homo sapiens | Human | PF00229 | 6.5 | IC50 | BindingDB |
| P24468 | NR2F2 | Homo sapiens | Human | PF00104 PF00105 | 6.1 | IC50 | ChEMBL;BindingDB |
| Q13285 | NR5A1 | Homo sapiens | Human | PF00104 PF00105 | 6.1 | IC50 | BindingDB |
| P35398 | RORA | Homo sapiens | Human | PF00104 PF00105 | 6.1 | IC50 | BindingDB |