Molecule Details
InChIKeyJXDYOSVKVSQGJM-UHFFFAOYSA-N
Compound NameJnj-26483327
Canonical SMILESCOc1cc2ncnc3c2cc1OCCCCCN(C)Cc1ccc(Br)cc1N3
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)7
Pfam Stratification Cross-Family
Avg pChEMBL7.38
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (7)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9Y243 AKT3 Homo sapiens Human PF00169 PF00069 PF00433 8.2 Kd ChEMBL
P12931 SRC Homo sapiens Human PF07714 PF00017 PF00018 8.0 IC50 ChEMBL;BindingDB
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 8.0 IC50 ChEMBL;BindingDB
Q15303 ERBB4 Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 8.0 IC50 ChEMBL;BindingDB
O14976 GAK Homo sapiens Human PF00069 PF10409 6.9 Kd ChEMBL
O43353 RIPK2 Homo sapiens Human PF00619 PF07714 6.4 Kd ChEMBL
P00533 EGFR Homo sapiens Human PF00757 PF14843 PF07714 PF01030 PF21314 6.2 Kd ChEMBL