Molecule Details
InChIKeyJWYIGNODXSRKGP-UHFFFAOYSA-N
Canonical SMILESCC(=O)Nc1cccc2c1c(Sc1ccc(Cl)cc1)c(C)n2CC(=O)O
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)2
Pfam Stratification Cross-Family
Avg pChEMBL7.23
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
DrugBank Annotations
DrugBank ID DB11946
Drug NameAZD-1981
CAS Number802904-66-1
Groups investigational
ATC Codes nan
DescriptionAZD1981 has been used in trials studying the treatment and basic science of Asthma, Postmenopausal, Pharmakokinetic, Asthma Patients, and Drug Interaction, among others.

Cross-references: BindingDB: 50357102 CHEMBL1914489 ChemSpider: 9467177 PubChem:11292191 PubChem:347828272 ZINC: ZINC000073196066
Target Activities (2)
Target Gene Organism Category Pfam pChEMBL Type Source
Q9Y5Y4 PTGDR2 Homo sapiens Human PF00001 8.4 IC50 ChEMBL;BindingDB
P15121 AKR1B1 Homo sapiens Human PF00248 6.1 IC50 ChEMBL;BindingDB
DrugBank Target Actions (1)
Target Gene Target Name Action Type
Q9Y5Y4 PTGDR2 Prostaglandin D2 receptor 2 antagonist targets