Molecule Details
InChIKeyJWQOJVOKBAAAAR-UHFFFAOYSA-N
Compound NameBay 61-3606
Canonical SMILESCOc1ccc(-c2cc3nccn3c(Nc3ncccc3C(N)=O)n2)cc1OC
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)29
Pfam Stratification Cross-Family
Avg pChEMBL6.88
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (29)
Target Gene Organism Category Pfam pChEMBL Type Source
P43405 SYK Homo sapiens Human PF07714 PF00017 8.1 Ki ChEMBL;BindingDB
Q9HAZ1 CLK4 Homo sapiens Human PF00069 8.0 Ki ChEMBL
Q12851 MAP4K2 Homo sapiens Human PF00780 PF00069 7.8 Ki ChEMBL
O00311 CDC7 Homo sapiens Human PF00069 7.7 Ki ChEMBL
P49841 GSK3B Homo sapiens Human PF00069 7.7 Ki ChEMBL
P51957 NEK4 Homo sapiens Human PF00069 7.6 Ki ChEMBL
O75116 ROCK2 Homo sapiens Human PF25346 PF00069 PF08912 7.5 Ki ChEMBL
O94806 PRKD3 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 7.5 Ki ChEMBL
P36888 FLT3 Homo sapiens Human PF00047 PF07714 7.4 Ki ChEMBL
P49840 GSK3A Homo sapiens Human PF00069 7.4 Ki ChEMBL
O95819 MAP4K4 Homo sapiens Human PF00780 PF00069 7.0 Ki ChEMBL
Q16513 PKN2 Homo sapiens Human PF02185 PF00069 PF00433 7.0 Ki ChEMBL
P49760 CLK2 Homo sapiens Human PF00069 6.9 Ki ChEMBL
Q00535 CDK5 Homo sapiens Human PF00069 6.9 Ki ChEMBL
Q9BZL6 PRKD2 Homo sapiens Human PF00130 PF00169 PF00069 PF25525 6.9 Ki ChEMBL
Q13464 ROCK1 Homo sapiens Human PF25346 PF00069 PF08912 6.7 Ki ChEMBL
Q96GD4 AURKB Homo sapiens Human PF00069 6.6 Ki ChEMBL
P10721 KIT Homo sapiens Human PF00047 PF07714 6.5 Ki ChEMBL
P24941 CDK2 Homo sapiens Human PF00069 6.5 Ki ChEMBL
P08581 MET Homo sapiens Human PF07714 PF01437 PF01403 PF01833 6.4 Ki ChEMBL
O43781 DYRK3 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P06493 CDK1 Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q13627 DYRK1A Homo sapiens Human PF00069 6.3 Ki ChEMBL
Q9H2X6 HIPK2 Homo sapiens Human PF00069 6.3 Ki ChEMBL
P07333 CSF1R Homo sapiens Human PF00047 PF25305 PF07714 6.2 Ki ChEMBL
Q9H2G2 SLK Homo sapiens Human PF00069 PF12474 6.1 Ki ChEMBL
P15735 PHKG2 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q9HBH9 MKNK2 Homo sapiens Human PF00069 6.0 Ki ChEMBL
Q9P1W9 PIM2 Homo sapiens Human PF00069 6.0 Ki ChEMBL