Molecule Details
InChIKeyJWILUIVAYLRFIY-UHFFFAOYSA-N
Compound NameN-[4-[[7-cyclopentyl-6-(dimethylcarbamoyl)pyrrolo[2,3-d]pyrimidin-2-yl]amino]phenyl]-N'-hydroxyoctanediamide
Canonical SMILESCN(C)C(=O)c1cc2cnc(Nc3ccc(NC(=O)CCCCCCC(=O)NO)cc3)nc2n1C1CCCC1
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)14
Pfam Stratification Cross-Family
Avg pChEMBL7.75
SourceChEMBL;BindingDB
2D Structure
2D structure
Activity Profile
Target Activities (14)
Target Gene Organism Category Pfam pChEMBL Type Source
Q13547 HDAC1 Homo sapiens Human PF00850 8.7 IC50 ChEMBL;BindingDB
P11802 CDK4 Homo sapiens Human PF00069 8.1 IC50 ChEMBL;BindingDB
P30281 CCND3 Homo sapiens Human PF02984 PF00134 8.1 IC50 ChEMBL
O60563 CCNT1 Homo sapiens Human PF00134 PF21797 8.1 IC50 ChEMBL;BindingDB
P50750 CDK9 Homo sapiens Human PF00069 8.1 IC50 ChEMBL
O14965 AURKA Homo sapiens Human PF00069 7.9 IC50 ChEMBL;BindingDB
Q96GD4 AURKB Homo sapiens Human PF00069 7.7 IC50 ChEMBL;BindingDB
Q9NQS7 INCENP Homo sapiens Human PF03941 PF12178 7.7 IC50 ChEMBL
Q9UQB9 AURKC Homo sapiens Human PF00069 7.7 IC50 ChEMBL;BindingDB
P04629 NTRK1 Homo sapiens Human PF13855 PF16920 PF07714 PF18613 7.5 IC50 ChEMBL;BindingDB
P35916 FLT4 Homo sapiens Human PF07679 PF13927 PF22971 PF07714 PF21339 PF17988 PF22854 7.4 IC50 ChEMBL;BindingDB
P53667 LIMK1 Homo sapiens Human PF00412 PF00595 PF07714 7.4 IC50 ChEMBL;BindingDB
Q96RR4 CAMKK2 Homo sapiens Human PF00069 7.3 IC50 ChEMBL;BindingDB
Q9UL54 TAOK2 Homo sapiens Human PF00069 7.1 IC50 ChEMBL;BindingDB