Molecule Details
| InChIKey | JWBACCHTZDUJCB-IOASZLSFSA-N |
|---|---|
| Compound Name | (1R,4R,5R)-4-[3-fluoro-4-(trifluoromethyl)phenyl]-2,2,6-trimethyl-3-azabicyclo[3.3.1]non-6-ene |
| Canonical SMILES | CC1=CC[C@@H]2C[C@H]1[C@H](c1ccc(C(F)(F)F)c(F)c1)NC2(C)C |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 5 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 6.38 |
| Source | ChEMBL |
2D Structure
Activity Profile
Target Activities (5)
| Target | Gene | Organism | Category | Pfam | pChEMBL | Type | Source |
|---|---|---|---|---|---|---|---|
| Q5BJF2 | TMEM97 | Homo sapiens | Human | PF05241 | 7.2 | Ki | ChEMBL |
| P35462 | DRD3 | Homo sapiens | Human | PF00001 | 6.3 | Ki | ChEMBL |
| P14416 | DRD2 | Homo sapiens | Human | PF00001 | 6.2 | Ki | ChEMBL |
| P36544 | CHRNA7 | Homo sapiens | Human | PF02931 PF02932 | 6.2 | IC50 | ChEMBL |
| P21917 | DRD4 | Homo sapiens | Human | PF00001 | 6.0 | Ki | ChEMBL |