Molecule Details
InChIKeyJVGBTTIJPBFLTE-UHFFFAOYSA-N
Compound NameSpiroxatrine
Canonical SMILESO=C1NCN(c2ccccc2)C12CCN(CC1COc3ccccc3O1)CC2
Clinical Status Data-mined Candidate
Targets (Human+Pathogen)16
Pfam Stratification Cross-Family
Avg pChEMBL7.37
SourceBindingDB;ChEMBL
2D Structure
2D structure
Activity Profile
Target Activities (16)
Target Gene Organism Category Pfam pChEMBL Type Source
P18825 ADRA2C Homo sapiens Human PF00001 9.2 Ki ChEMBL;BindingDB
P18089 ADRA2B Homo sapiens Human PF00001 8.8 Ki ChEMBL;BindingDB
P08908 HTR1A Homo sapiens Human PF00001 8.7 Ki ChEMBL;BindingDB
P14416 DRD2 Homo sapiens Human PF00001 8.2 Ki ChEMBL
P35462 DRD3 Homo sapiens Human PF00001 8.1 Ki ChEMBL
P08913 ADRA2A Homo sapiens Human PF00001 8.0 Ki ChEMBL;BindingDB
P35372 OPRM1 Homo sapiens Human PF00001 7.9 Ki ChEMBL
P21917 DRD4 Homo sapiens Human PF00001 7.7 Ki ChEMBL
P34969 HTR7 Homo sapiens Human PF00001 7.2 Ki ChEMBL
P25100 ADRA1D Homo sapiens Human PF00001 6.9 Ki ChEMBL
P35368 ADRA1B Homo sapiens Human PF00001 6.5 Ki ChEMBL
P35348 ADRA1A Homo sapiens Human PF00001 6.3 Ki ChEMBL
P41595 HTR2B Homo sapiens Human PF00001 6.3 Ki BindingDB
P28223 HTR2A Homo sapiens Human PF00001 6.2 Ki ChEMBL
P41145 OPRK1 Homo sapiens Human PF00001 6.2 Ki ChEMBL
Q5BJF2 TMEM97 Homo sapiens Human PF05241 6.0 Ki ChEMBL