6-Methyl-3-(1H-pyrazol-4-yl)-N-[3-[(3,3,4,4-tetrafluoro-1-pyrrolidinyl)methyl]-5-isothiazolyl]imidazo[1,2-a]pyrazin-8-amine Hydrochloride

InChIKey	`JUXJSIGKLXPRRY-UHFFFAOYSA-N`
Compound Name	6-Methyl-3-(1H-pyrazol-4-yl)-N-[3-[(3,3,4,4-tetrafluoro-1-pyrrolidinyl)methyl]-5-isothiazolyl]imidazo[1,2-a]pyrazin-8-amine Hydrochloride
Canonical SMILES	`Cc1cn2c(-c3cn[nH]c3)cnc2c(Nc2cc(CN3CC(F)(F)C(F)(F)C3)ns2)n1`
Clinical Status	Clinical Multi-Target
Targets (Human+Pathogen)	2
Pfam Stratification	Homologous
Avg pChEMBL	7.85
Source	ChEMBL;BindingDB;TTD_MultiTarget

2D Structure

Activity Profile

Target	Gene	Organism	Category	Pfam	pChEMBL	Type	Source
O75716	STK16	Homo sapiens	Human	PF00069	8.4	pIC50	TTD_MultiTarget
Q96GD4	AURKB	Homo sapiens	Human	PF00069	7.3	IC50	ChEMBL;BindingDB