Molecule Details
| InChIKey | JUVIOZPCNVVQFO-HBGVWJBISA-N |
|---|---|
| Compound Name | Rotenone |
| Canonical SMILES | C=C(C)[C@H]1Cc2c(ccc3c2O[C@@H]2COc4cc(OC)c(OC)cc4[C@@H]2C3=O)O1 |
| Clinical Status | Data-mined Candidate |
| Targets (Human+Pathogen) | 2 |
| Pfam Stratification | Cross-Family |
| Avg pChEMBL | 7.34 |
| Source | ChEMBL;BindingDB |
2D Structure
Activity Profile
DrugBank Annotations
| DrugBank ID | DB11457 |
|---|---|
| Drug Name | Rotenone |
| CAS Number | 83-79-4 |
| Groups | experimental vet_approved |
| ATC Codes | nan |
| Description | Rotenone is an isoflavone compound that naturally occurs in the jicama vine plant as well as many Fabaceae plants. It has broad spectrum insecticide and pesticide activity and is also toxic to fish. |
Categories: Agrochemicals Benzopyrans Chromones Compounds used in a research, industrial, or household setting Enzyme Inhibitors Flavonoids Heterocyclic Compounds, Fused-Ring Insecticides Isoflavones Pesticides Pyrans Toxic Actions Uncoupling Agents
Cross-references: BindingDB: 50135527 ChEBI: 28201 CHEMBL429023 ChemSpider: 6500 C07593 PDB: 970 PubChem:6758 PubChem:347827979 RxCUI: 1366666 Wikipedia: Rotenone ZINC: ZINC000003860715